Ace Infectious provides H. pylori adhesin research services to help study the structure, adhesion sites, immune response, and potential role of H. pylori adhesins.
Currently, H. pylori adhesins are known to adhere to small molecules (e.g., sugars) and larger ligands (e.g., proteins) of host cells. Some of these adhesins are more clearly studied. CagL interacts with the α5β1, αVβ3, αVβ5, and αVβ6 of host cells. HopQ interacts with CEACAM -1, -3, -5, and -6 of host cells. BabA, HopD, and SabA interact with mucins of host cells by blood group antigens (Leb, A- Leb, and B-Leb), sialyated Lex, and asialyated Lex. In addition, SabA also interacts with sialyated Lex and asialyated Lex of laminin. AlpA and AlpB also bind to laminin. However, the specific adhesion profiles of HorB, HomA/B/C/D, OipA, and HopZ need to be further explored. Learn more：H. pylori adhesion regulation
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