The tumor microenvironment (TME) plays a crucial role in cancer progression and therapy response. It encompasses a complex network of interactions between malignant and non-transformed cells, including blood vessels, immune cells, fibroblasts, signaling molecules, and the extracellular matrix (ECM). Understanding TME and its associated pathways is essential for developing effective therapeutic strategies. Alfa Oncology provides a range of TME pathway-associated products for customers, including antibodies, proteins, and ELISA kits to help them understand TME and related pathways.

Angiogenesis-Related Factors Angiogenesis, the process of forming new blood vessels from the development of existing capillaries or postcapillary veins, is essential for the growth and spread of cancer tumors. It involves the release of certain factors that stimulate the formation of vascular networks that provide nutrients and oxygen to the tumor. Since tumor growth and metastasis are dependent on angiogenesis, inhibition of angiogenesis may hinder tumor progression and restrict its ability to metastasize. Scientists have discovered various angiogenesis inhibitors, and these hold potential as effective treatments for cancer. In addition, the formation and development of blood vessels rely on a delicate balance between factors that promote and inhibit angiogenesis. There are numerous proteins known as angiogenesis activators, such as basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF), and angiopoietin. These proteins play vital roles in stimulating the process of angiogenesis in various physiological and pathological conditions. Learn more：intracellular signaling factors