Immune checkpoints are regulators to enhance or moderate immune responses. Immune checkpoint mechanisms are often activated to suppress the nascent anti-tumor immune response, which leads to the development of several immune checkpoint inhibitors, such as antibodies, peptides, and small molecular drugs for cancer therapy. Combined with broad technological expertise and the latest instrumentation, Creative Biolabs is dedicated to offering a wide range of immune checkpoint development services, including antibodies, proteins, peptides, assays, small molecular drugs, and more. Our experienced team can also save you time by providing customer service to meet your specifications. Learn more: benefits of immune checkpoint inhibitors
James Parkinson revealed a detailed description of six patients with shaking palsy in 1817 and after his death, the mentioned description known as Parkinson's disease (PD), which is now the most common neurodegenerative disorder after Alzheimer's disease. The pathological hallmark of PD is the degeneration of dopaminergic neurons of the substantia nigra pars compacta (SNpc). The loss of this neuronal population results in functional imbalances in the nigrostriatal pathway, leading to lowering the level of dopamine (DA) in the striatum. Learn more: Parkinson's Disease Models
As a long-term expert in the field of macrophage polarization, Creative Biolabs has lots of scientists who are proficient at performing M1 macrophage polarization assay. Our seasoned scientists are pleased to share expertise and experience with our global clients and facilitate their meaningful macrophage polarization studies.
In the nervous system, to maintain the efficiency of axons transmitting information over long distances in the form of electrical pulses, the myelin is required to wrap around the axon. Myelin is a lipid-rich specialized membrane generated by glial cells. In the central nervous system (CNS), myelin is generated from glial cells, which are also called oligodendrocytes. Learn more: oligodendrocyte development
A fluorometer (and fluorimeter) measures the fluorescence or light emitted by different fluorescing objects. Fluorescence occurs when light of specific wavelength hits and excites electrons in a sample, and the electrons in that sample instantly emit or fluoresce light of a different wavelength. All fluorescent objects have its own fingerprint, meaning that it excites and emits predictable types of light. Analytical measurements provided by Fluorescence Spectroscopy Instrumentation are used in multiple applications including chemistry/biochemistry, medicine, pharmaceuticals, food science, environmental studies and nanotechnology. Fluorescence spectroscopy instruments have been used to examine counterfeit banknotes, materials for optoelectronics, and proteins.
A fluorometer (and fluorimeter) measures the fluorescence or light emitted by different fluorescing objects. Fluorescence occurs when light of specific wavelength hits and excites electrons in a sample, and the electrons in that sample instantly emit or fluoresce light of a different wavelength. All fluorescent objects have its own fingerprint, meaning that it excites and emits predictable types of light. Analytical measurements provided by Fluorescence Spectroscopy Instrumentation are used in multiple applications including chemistry/biochemistry, medicine, pharmaceuticals, food science, environmental studies and nanotechnology. Fluorescence spectroscopy instruments have been used to examine counterfeit banknotes, materials for optoelectronics, and proteins.
raphitic carbon nitride (g-C3N4) is a planar two-dimensional sheet structure similar to graphene, with two basic units, based on triazine ring (C3N3) and 3-s-triazine ring (C6N7) respectively the structural units extend infinitely to form a network structure, and the two-dimensional nanosheets are combined by van der Waals forces. g-C3N4 has become an important material in the fields of chemistry, physics, and medicine due to its simple preparation method, low cost, environmental friendliness, good stability, and good physical and chemical properties. The most common precursors used to prepare g-C3N4 are melamine, dicyandiamide, cyanamide, urea, thiourea, and ammonium thiocyanate. To enhance the performance and tuning properties of g-C3N4, heterojunctions can be doped and fabricated with other materials. Among these materials can be metal oxides, metal sulfides, noble metals and carbon nanomaterials. Among them, metal oxides are the most common method to improve the efficiency of g-C3N4. The g-C3N4 structure has been widely used in many applications, and in addition to energy-related applications, its application in the field of drug delivery has also received increasing attention from scientists. Studies have shown that g-C3N4 is an effective nanocarriers and can be used for the delivery of many drugs. The adsorption energy of g-C3N4 is about high, and the high adsorption energy indicates that g-C3N4 can form stable complexes with the loaded drugs. The resulting complex system has a higher dipole moment value, which improves the solubility of the complex. Furthermore, after the complex formation of g-C3N4 and the drug, its higher hydrophilicity facilitates drug transfer in the in vivo physiological environment.
CD Bioparticles manufactures and supplies g-C3N4. Contact us to find out how g-C3N4 can help you in your work.
Color-dyes polystyrene particles conjugated with recognition molecules as antibodies, antigens, proteins, or other biomacromolecules are available on request. Unmodified polymer spheres are also offered. These polymer particles find extensive applications in a range of flow assays, diagnostic tests, optical and electronic instrument testing, and calibration.
Color Rich Dyed Latex Particles
Color-dyes polystyrene particles conjugated with recognition molecules as antibodies, antigens, proteins, or other biomacromolecules are available on request. Unmodified polymer spheres are also offered. These polymer particles find extensive applications in a range of flow assays, diagnostic tests, optical and electronic instrument testing, and calibration.
Atherosclerosis is the most common type of vascular disease; it starts from the lesion of intima. Generally, there are lipid and complex carbohydrate accumulation, hemorrhage and thrombosis, fibrous tissue hyperplasia and calcinosis, and gradual metamorphosis and calcification of the middle layer of the artery. The lesion often involves large and medium muscular arteries, once developed enough to block the arterial lumen, the tissue or organ supplied by the artery will be ischemic or necrotic. Atherosclerosis is the most common and important disease in atherosclerotic vascular disease. It is the main pathological basis of ischemic cardiovascular and cerebrovascular diseases such as coronary atherosclerotic heart disease (CHD) and cerebrovascular disease. Among them, cardiovascular disease is the main cause of death worldwide, and the most influential is atherosclerotic cardiovascular disease.