Atherosclerosis is the most common type of vascular disease; it starts from the lesion of intima. Generally, there are lipid and complex carbohydrate accumulation, hemorrhage and thrombosis, fibrous tissue hyperplasia and calcinosis, and gradual metamorphosis and calcification of the middle layer of the artery. The lesion often involves large and medium muscular arteries, once developed enough to block the arterial lumen, the tissue or organ supplied by the artery will be ischemic or necrotic. Atherosclerosis is the most common and important disease in atherosclerotic vascular disease. It is the main pathological basis of ischemic cardiovascular and cerebrovascular diseases such as coronary atherosclerotic heart disease (CHD) and cerebrovascular disease. Among them, cardiovascular disease is the main cause of death worldwide, and the most influential is atherosclerotic cardiovascular disease.
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