The goal was to develop a platform that could program comprehensive biosynthesis development in one place, and since then, it has become a reality. The Synthetic Biology Platform is a disruptive technology platform focusing on synthetic biology, which can contribute to the advancement of diverse areas, including but not limited to industrial biotechnology, pharmaceutical, agriculture, and healthcare research.

The Synthetic Biology Platform integrates engineering principles and a broad range of methodologies from various disciplines, such as biology, bioinformatics, chemistry, physics, mathematics, and computer science. It’s designed to perform strain-based chassis engineering as well as biosynthesis development for various molecules, thus gaining insights into disease mechanisms, identifying novel drug targets, and accelerating drug discovery and development.

Combining the very robust technologies of CRISPR, microfluidic, nanotechnology, omics, and bioinformatics, the Synthetic Biology Platform reaches beyond traditional technology applications, providing cutting-edge synthetic and analytical tools, as well as elucidating the biology and chemistry functionalities. Instead of following a narrow, vertical structure, it embraces a platform-based model, and its synthetic biology toolboxes can help researchers accelerate the design and construction of new biological entities or the re-design of natural biological processes and pathways through the iterative Design-Build-Test-Learn (DBTL) cycles when utilizing the Synthetic Biology Platform.

The Synthetic Biology Platform offers reliable biosynthesis development for a large selection of chemicals, natural compounds, industrial enzymes, etc., which could seamlessly integrate into the subsequent workflows, thus greatly accelerating workflow efficiency. In addition, the Synthetic Biology Platform is able to achieve appropriate chassis engineering for gene editing, gene mutation, and many other applications. More importantly, it is capable of designing, building, testing, and learning together to streamline and standardize the whole project process, including FUT8 knockout, host selection, modeling, genetic engineering, sequencing, and data analysis.

Not to mention, the Synthetic Biology Platform consists of modules designed to provide scientists with an intuitive, easy-to-use, and comprehensive set of tools that come seamlessly together to form an enterprise-ready scientific informatics platform. With powerful capabilities and flexibility, it can support and facilitate the applications of synthetic biology in a wide range of areas. Meanwhile, it also can be customized to tailor solutions according to researchers’ unique and innovative demands. In other words, everything they need – in one place.

About the Synthetic Biology Platform Synthetic Biology Platform is a state-of-the-art solution platform for scientific research and discovery. Its flexibility can meet all demands of the synthetic biology industry and those of various business units in R&D organizations today, thus rapidly adapting and scaling to meet whatever requirements researchers may raise.

The Synthetic Biology Platform is a comprehensive toolbox and fully integrated platform to empower synthetic biology research and development.

Synthetic biology is an emerging interdisciplinary field that combines principles of engineering and biology to create artificial lives or re-design organisms for useful purposes. In fact, designing a platform that could carry out full-scale biosynthesis development from chemicals to enzymes in one place can save much cost and time for synthetic biology researchers. Given the need, a cutting-edge Synthetic Biology Platform is developed to offer technical support for the development of synthetic biology applications.

The Synthetic Biology Platform integrated with the CRISPR technology can regulate gene expression needed for synthetic biology more efficiently and precisely. Complex genetic circuits based on CRISPR allow for more accurate regulation of gene expression in terms of expression levels and timing than traditional methods. Besides, combined with microfluidic technologies, the Platform allows for precise environmental control while capturing high-quality data. Ever since the introduction of the first synthetic genetic circuit, the development of synthetic biology and microfluidics have been intertwined. Hence, in utilizing the Synthetic Biology Platform, researchers can not only achieve low-cost and high-yield biosynthesis of specific products by incorporating a precision fermentation process but also take advantage of the robust integrated tools, such as omics, bioinformatics, and nanotechnology, that elevate the Synthetic Biology Platform beyond conventional technological applications.

With powerful capabilities and flexibility, on the one hand, the Synthetic Biology Platform can select an appropriate framework for research, including minimal genomes, bacterial chassis, cell-free synthetic biology chassis, and many others, for the next generation of synthetic biology chassis to display biological complexity and predict behaviors. On the other hand, the platform can improve the yield of chemicals, amino acids, peptides, proteins, and enzymes using genome editing, microbial fermentation, and many other synthetic biology strategies.

Synthetic Biology Platform is able to offer a wide range of enabling technologies and a comprehensive synthetic biology toolbox to help researchers accelerate the design and construction of new biological entities or the re-design of natural biological processes through the iterative Design-Build-Test-Learn (DBTL) cycles of synthetic biology. This system is dedicated to assisting synthetic biology researchers around the world with custom synthetic biology services and effective strategies. Learn more: hNMI knockout

About the Synthetic Biology Platform The Synthetic Biology Platform is a state-of-the-art solution platform for scientific research and discovery. Its flexibility can meet all demands of the synthetic biology industry and those of various business units in R&D organizations today, thus rapidly adapting and scaling up to meet whatever requirements researchers may raise.

Gene editing, one of the key tools in synthetic biology, allows scientists to manipulate the DNA of organisms to create new functions, optimize metabolic pathways, and engineer new traits. In recent years, the development of new gene editing tools, such as CRISPR-Cas9, has made gene editing faster, cheaper, and more precise than ever before.

Methods for gene editing CRISPR-Cas9 CRISPR-Cas9 is a revolutionary gene editing tool that uses a molecular complex composed of a guide RNA (gRNA) and a Cas9 protein. The gRNA guides the Cas9 protein to a specific location in the genome where it can make a double-stranded break. This break is then repaired by the cell's own DNA repair machinery, which can introduce desired genetic changes.

Multiplex Genome Editing by Natural Transformation (MuGENT) MuGENT is a gene editing method that utilizes the natural transformation process in bacterial cells to introduce multiple edits into the genome simultaneously. This technique is particularly useful for making multiple changes in the bacterial genome without the need for complex molecular biology techniques.

Genome synthesis Genome synthesis is the process of creating artificial DNA sequences in a laboratory. This technique is highly valuable for gene editing as it allows scientists to design and engineer synthetic genes or whole genomes for various purposes, including gene therapy, drug development, and studying genetic diseases.

Homologous Recombination (HR) Homologous recombination is a natural DNA repair process that can be harnessed for gene editing. In this method, a piece of DNA containing the desired genetic changes is introduced into the cell, and the cell uses its homologous recombination machinery to incorporate this DNA into the genome, replacing the target sequence.

Each of these gene editing methods has its advantages and limitations, and the choice of method depends on the specific requirements of the research or application. CD Biosynsis has years of experience in gene editing, strain engineering and enzymogenius enzyme engineering. Their experts use the latest tools and techniques to ensure that their services are precise, efficient, and cost-effective. Whether researchers are developing new strains for biotechnology, agriculture, or medicine, the company can help clients achieve their goals and drive innovation in their industry.

Our Microbial Genetic Engineering service offers cutting-edge solutions for manipulating and modifying microbial genomes. With our expertise in genetic engineering technologies, we enable clients to harness the potential of microbes for various applications in industries such as healthcare, agriculture, environmental remediation, and bioproduction. By leveraging the power of genetic engineering, we provide innovative solutions that address specific challenges and unlock new opportunities in these industries. Source from: Microbial genetic engineering solutions

Site-Directed Mutagenesis is a powerful molecular biology technique used to introduce specific changes in the DNA sequence of a gene. It allows researchers to create precise mutations at desired locations in the genome, enabling the study of gene function, protein structure, and various biological processes.

By manipulating the DNA sequence, researchers can investigate the impact of specific mutations on protein function, study disease-causing mutations, and even engineer new proteins with improved properties. This technique has revolutionized the field of molecular biology and has become an indispensable tool for genetic engineering projects.

Reference: q5 site directed mutagenesis

Experience the future of synthetic biology with our One-Stop Services, where innovation and convenience converge. From design to build, test, and learn, our platform covers every aspect of your synthetic biology project lifecycle—simplify your journey to groundbreaking discoveries with our unified, cutting-edge solutions. Learn more：Synthetic Biology Applications

RNA molecules play crucial roles in various biological processes, including gene expression, regulation, and protein synthesis. By modifying RNA molecules, researchers can gain insights into the fundamental mechanisms of these processes and develop innovative applications in fields such as therapeutics, diagnostics, and biotechnology. Learn more：Custom RNA Modifications

EnzymoGenius™ stands at the forefront of cutting-edge enzyme engineering, leveraging advanced AI-driven technologies to tailor enzymes with precision and finesse. Specializing in the meticulous alteration of stereochemistry, our service opens new frontiers in biocatalysis.

Overview Current research in enzyme engineering with altered stereochemistry is marked by significant strides and emerging trends. The intricate manipulation of enzyme structures has unveiled novel catalytic possibilities, enabling the synthesis of chiral compounds with unprecedented efficiency. Advances in directed evolution techniques have enabled the tailoring of enzyme stereoselectivity, offering precise control over reaction outcomes. Additionally, the integration of computational approaches, such as molecular modeling and simulation, has accelerated the design of enzymes with desired stereochemical features. Furthermore, the exploration of non-natural substrates and cofactors has expanded the catalytic repertoire of engineered enzymes. As researchers delve deeper into these frontiers, the prospect of developing catalysts for diverse bioconversion processes and pharmaceutical applications becomes increasingly promising, paving the way for innovative solutions in synthetic biology and industrial biotechnology. Learn more：Engineering Enzymes with Altered Stereochemistry

Golden Gate Assembly Service is a specialized service offered by our company. It is a powerful molecular biology technique used for DNA assembly and genetic engineering. With our expertise and advanced equipment, we can provide efficient and reliable Golden Gate Assembly solutions tailored to your specific needs. Whether you are working on a small-scale project or a large-scale research endeavor, our Golden Gate Assembly Service can support your DNA assembly requirements.