john swift at September 07, 2024 at 12:20am PDT

We, as a leading preclinical contract research organization (CRO), have been at the forefront of scientific advancements for decades. We focus on providing preclinical solutions that deliver client studies with responsiveness, flexibility, and customized approaches. By delving into different therapeutic areas, we help clients understand the challenges faced in each and explore potential avenues for pharmaceutical intervention.

More information: Aging-associated diseases

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We employ advanced techniques to gain comprehensive insights into the molecular mechanisms underlying aging processes. We are committed to accelerating progress in the field of aging-related diseases, striving to advance the discovery of treatments and therapeutics for a wide spectrum of conditions such as Alzheimer's disease, osteoporosis, arthritis, Parkinson's disease, cardiovascular diseases, and aging-related macular degeneration. Learn more:Professional Aging Research Application

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Our WMicroTracker systems allow automatic readings of the behavior of C. elegans. Our systems bring disruptive innovation in the measurement of compound toxicity, resistance to stress, search for new anthelmintics, metabolic, lifetime, and human disease models.

The micro-tracker is an automated system that provides quantitative measurements of a variety of parameters such as movement patterns, velocity, directionality, and response to stimuli. The multiple infrared microbeam of our micro-tracker allows for real-time tracking and analysis of multiple organisms at the same time, resulting in efficient and high-throughput data collection. In addition, the micro-tracker's non-invasive tracking technology minimizes stress and interference with the organisms, ensuring more accurate and reliable data. Learn more:worm tracker

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Intact membrane proteins are exposed to a complex and dynamic lipid environment regulated by nonbilayer lipids, which can have an impact on protein functions through lipid-protein interactions. In plant photosynthetic thylakoid membranes, the most abundant lipid is the non-bilayer lipid monogalactosyl diacylglycerol (MGDG), but no studies have yet clearly elucidated the effect of MGDG on the function of energy-converting membrane protein complexes.

Exploring the physical properties of thylakoid membrane lipids has implications for photosynthesis research in several areas, such as lipoprotein interactions in the context of the structure and function of major photosynthetic membrane complexes, lipid phase behavior and its relevance to membrane phase separation, and membrane fluidity in terms of thermal adaptation and factors limiting electron transport rates. Therefore, a deeper understanding of lipid polymorphism in chloroplast thylakoid membranes and the conformational dynamics of lipids is of great importance for the study of photosynthesis. Learn more:kinetic analysis services of lipids in photosynthetic thylakoid membranes

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